17-oh Progesterone belongs to a group of steroid hormones produced by the adrenal glands, the placenta, the corpus luteum, mature follicles and sex glands.This hormone is synthesized in the body of men and women, and is a precursor of cortisol, testosterone and estradiol.In the female body 17-oh progesterone is responsible for the regulation of the menstrual cycle and sexual function, affects fertility and childbearing.The level of this hormone in women can fluctuate significantly depending on the phase of the menstrual cycle and pregnancy.In premenopausal and menopause have low maintenance 17-oh progesterone in the blood.

Fluctuations 17-oh progesterone in the body

During the day the level of a hormone in the body is constantly changing: the highest concentration observed in th
e morning, and the minimum - at night.In women, levels of this hormone rises on the eve of ovulation, decreases in the follicular phase and reaches a minimum in the phase of ovulation.

if conception occurred and the attachment of the embryo to the uterine wall, the content of the hormone in the blood begins to gradually increase.During pregnancy, the synthesis of the steroid hormone "connected" and the placenta.

level of acceptable values ​​17-oh progesterone depending on the duration of pregnancy:
- first trimester: 3,55-17,03 nmol / L;
- second trimester: 3,55-20 nmol / L;
- the third trimester: 3,75-33,33 nmol / L.

What threatens to increase the level of progesterone 17-oh

Normally, increasing 17-oh progesterone occurs only during pregnancy, other times it indicates the presence of any pathology.Determine the level of the hormone by examining the blood plasma or serum by enzyme immunoassay.Research is usually prescribed in the following cases:
- in violation of the menstrual cycle;
- infertility, spontaneous abortion;
- for suspected tumor of the adrenal glands and ovaries;
- when hirsutism (increased body hair on the male pattern).

analysis results allow a correct diagnosis and correct therapy.Sometimes patients have a decrease in the level of progesterone 17-oh - this condition occurs in Addison's disease, acquired or congenital adrenal insufficiency.In men, hormone levels may decrease due to violation progersterona synthesis, which leads to the development of false hermaphroditism.